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Countdown to concluded its tasks after
2019-05-08

Countdown to 2015 concluded its tasks after the launch of its seventh global report at the Maternal Newborn Health conference in Mexico City, October, 2015. It is now relaunched as Countdown to 2030 (CD2030), retaining and enhancing the successful multi-institutional network with over a decade of he
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The circadian variation of VF shows
2019-05-08

The circadian variation of VF shows a similar nocturnal pattern in patients with BS and ERS [32] (Fig. 2). This is in contrast to the circadian pattern of VTAs in patients with ischemic heart diseases [33]. In a Korean cohort of patients with ERS and BS who underwent implantable cardioverter defibri
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pim inhibitor In patients with surgically corrected CHD the
2019-05-08

In patients with surgically corrected CHD, the anatomic position of the atriotomy scar as the arrhythmogenic substrate is commonly found in the free wall and not in the septum [8]. The cause of this large area of low voltage (“atrial myopathy”) is unclear. Possible explanations include interruption
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br Discussion Treatment of patients with
2019-05-08

Discussion Treatment of patients with vaginal leiomyosarcoma is challenging because of the rarity of this disease and a lack of controlled clinical trials comparing management strategies. At this time primary surgery remains the mainstay of management of vaginal leiomyosarcoma. Treatment plans sh
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Adhesive interactions Adhesive interactions between myeloma
2019-05-08

Adhesive interactions: Adhesive interactions between myeloma FK866 and stromal cells play a significant role in both the homing of MM cells to the bone marrow and augmentation of the bone destructive process. These adhesive interactions result in activation of NF-κB and p38 MAP-kinase signaling, w
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The standard therapy for chordoma is excision Local
2019-05-08

The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c
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br Introduction Once metastatic breast cancer cells
2019-05-08

Introduction Once metastatic breast cancer FLAG Peptide are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade the
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br La flor de Coleridge En el
2019-05-07

La flor de Coleridge En el ensayo de ese nombre contenido en Otras inquisiciones leemos: De inmediato, y como corolario de estas ideas, nuestro ensayista da un salto para instalarnos en un mundo donde esta probabilidad se cumple: Como en el universo de Tlön, y siguiendo las premisas del idealis
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Ante la falta de un
2019-05-07

Ante la falta de un ambiente estimulante para la producción de un pensamiento crítico y una conciencia social, Pablo Molinet (1975) escribe: “Quizá nuestra época nos dejó hablando solos” (93). No es de extrañar: luego de 1968, las concentraciones de jóvenes fueron vistas como un peligro y se dispuso
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br Conflict of interest br Acknowledgments This research was
2019-05-07

Conflict of interest Acknowledgments This research was supported by the Grants from the National Natural Science Foundation of China (No. 31270820 and No. 81230061 to Wei-Dong Han, No. 81402567 to Ya-jing Zhang) and was partially supported by a Grant from the National Basic Science and Develop
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The authors would like to thank Ms Fang
2019-05-07

The authors would like to thank Ms. Fang-Ju Sun for her help with statistical analysis. This study was supported by a research grant from Mackay Memorial Hospital (MMH10466). Introduction Cancer of the GW788388 (CC) is the second most common cancer affecting women worldwide, and about 86% of CC
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Lomefloxacin HCl Supplier It is established that hypoxia can
2019-05-07

It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 Lomefloxacin HCl Supplier after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue section
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br Future perspectives Identification of LOX
2019-05-07

Future perspectives Identification of LOX as a modulator of the ECM to form pre-metastatic niches and subsequently bone metastasis arose as we were investigating the hypoxia tumour secretome using existing patient cohort data and cutting edge proteomics. Although condoned by some researchers as “
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We did not identify age as
2019-05-07

We did not identify age as a major factor shaping continuing HCV transmission and future seroprevalence. With every blood-borne disease, these epidemiological variables depend on how frequently individuals undergo medical procedures and the risk of acquiring HCV in each case. In our study, we used d
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br We welcome the efforts
2019-05-07

We welcome the efforts by Robert Cohen and colleagues to promote country-specific targets for post-2015 health goals. Publications from the Consortium of Universities for Global Health () conference included a welcome focus on the building of effective global health education programmes. Histor
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